HIV UTR, LTR, and Epigenetic Immunity

The duel between humans and viruses is unending. In this review, we examine the HIV RNA in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal repeat (LTR), and the immunity of human DNA in a format of epigenetic regulation. We explore the ways in which the hu...

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Detalles Bibliográficos
Autores principales: Zhang, Jielin, Crumpacker, Clyde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146425/
https://www.ncbi.nlm.nih.gov/pubmed/35632825
http://dx.doi.org/10.3390/v14051084
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author Zhang, Jielin
Crumpacker, Clyde
author_facet Zhang, Jielin
Crumpacker, Clyde
author_sort Zhang, Jielin
collection PubMed
description The duel between humans and viruses is unending. In this review, we examine the HIV RNA in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal repeat (LTR), and the immunity of human DNA in a format of epigenetic regulation. We explore the ways in which the human immune responses to invading pathogenic viral nucleic acids can inhibit HIV infection, exemplified by a chromatin vaccine (cVaccine) to elicit the immunity of our genome—epigenetic immunity towards a cure.
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spelling pubmed-91464252022-05-29 HIV UTR, LTR, and Epigenetic Immunity Zhang, Jielin Crumpacker, Clyde Viruses Review The duel between humans and viruses is unending. In this review, we examine the HIV RNA in the form of un-translated terminal region (UTR), the viral DNA in the form of long terminal repeat (LTR), and the immunity of human DNA in a format of epigenetic regulation. We explore the ways in which the human immune responses to invading pathogenic viral nucleic acids can inhibit HIV infection, exemplified by a chromatin vaccine (cVaccine) to elicit the immunity of our genome—epigenetic immunity towards a cure. MDPI 2022-05-18 /pmc/articles/PMC9146425/ /pubmed/35632825 http://dx.doi.org/10.3390/v14051084 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Jielin
Crumpacker, Clyde
HIV UTR, LTR, and Epigenetic Immunity
title HIV UTR, LTR, and Epigenetic Immunity
title_full HIV UTR, LTR, and Epigenetic Immunity
title_fullStr HIV UTR, LTR, and Epigenetic Immunity
title_full_unstemmed HIV UTR, LTR, and Epigenetic Immunity
title_short HIV UTR, LTR, and Epigenetic Immunity
title_sort hiv utr, ltr, and epigenetic immunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146425/
https://www.ncbi.nlm.nih.gov/pubmed/35632825
http://dx.doi.org/10.3390/v14051084
work_keys_str_mv AT zhangjielin hivutrltrandepigeneticimmunity
AT crumpackerclyde hivutrltrandepigeneticimmunity

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