A Therapeutically Active Minibody Exhibits an Antiviral Activity in Oseltamivir-Resistant Influenza-Infected Mice via Direct Hydrolysis of Viral RNAs

Emerging Oseltamivir-resistant influenza strains pose a critical public health threat due to antigenic shifts and drifts. We report an innovative strategy for controlling influenza A infections by use of a novel minibody of the 3D8 single chain variable fragment (scFv) showing intrinsic viral RNA hy...

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Detalles Bibliográficos
Autores principales: Lee, Yongjun, Hoang, Phuong Thi, Kim, Dongjun, Ayun, Ramadhani Qurrota, Luong, Quynh Xuan Thi, Na, Kyungho, Kim, Taehyun, Oh, Yeonsu, Kim, Won-Keun, Lee, Sukchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146509/
https://www.ncbi.nlm.nih.gov/pubmed/35632846
http://dx.doi.org/10.3390/v14051105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146509/
https://www.ncbi.nlm.nih.gov/pubmed/35632846
http://dx.doi.org/10.3390/v14051105

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