Cargando…

Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East

Dietary arsenic (As) contamination is a major public health issue. In the Middle East, the food supply relies primarily on the import of food commodities. Among different age groups the main source of As exposure is grains and grain-based food products, particularly rice and rice-based dietary produ...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Mohammad Idreesh, Ahmad, Md Faruque, Ahmad, Irfan, Ashfaq, Fauzia, Wahab, Shadma, Alsayegh, Abdulrahman A., Kumar, Sachil, Hakeem, Khalid Rehman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146532/
https://www.ncbi.nlm.nih.gov/pubmed/35631276
http://dx.doi.org/10.3390/nu14102136
_version_ 1784716586445176832
author Khan, Mohammad Idreesh
Ahmad, Md Faruque
Ahmad, Irfan
Ashfaq, Fauzia
Wahab, Shadma
Alsayegh, Abdulrahman A.
Kumar, Sachil
Hakeem, Khalid Rehman
author_facet Khan, Mohammad Idreesh
Ahmad, Md Faruque
Ahmad, Irfan
Ashfaq, Fauzia
Wahab, Shadma
Alsayegh, Abdulrahman A.
Kumar, Sachil
Hakeem, Khalid Rehman
author_sort Khan, Mohammad Idreesh
collection PubMed
description Dietary arsenic (As) contamination is a major public health issue. In the Middle East, the food supply relies primarily on the import of food commodities. Among different age groups the main source of As exposure is grains and grain-based food products, particularly rice and rice-based dietary products. Rice and rice products are a rich source of core macronutrients and act as a chief energy source across the world. The rate of rice consumption ranges from 250 to 650 g per day per person in South East Asian countries. The source of carbohydrates through rice is one of the leading causes of human As exposure. The Gulf population consumes primarily rice and ready-to-eat cereals as a large proportion of their meals. Exposure to arsenic leads to an increased risk of non-communicable diseases such as dysbiosis, obesity, metabolic syndrome, diabetes, chronic kidney disease, chronic heart disease, cancer, and maternal and fetal complications. The impact of arsenic-containing food items and their exposure on health outcomes are different among different age groups. In the Middle East countries, neurological deficit disorder (NDD) and autism spectrum disorder (ASD) cases are alarming issues. Arsenic exposure might be a causative factor that should be assessed by screening the population and regulatory bodies rechecking the limits of As among all age groups. Our goals for this review are to outline the source and distribution of arsenic in various foods and water and summarize the health complications linked with arsenic toxicity along with identified modifiers that add heterogeneity in biological responses and suggest improvements for multi-disciplinary interventions to minimize the global influence of arsenic. The development and validation of diverse analytical techniques to evaluate the toxic levels of different As contaminants in our food products is the need of the hour. Furthermore, standard parameters and guidelines for As-containing foods should be developed and implemented.
format Online
Article
Text
id pubmed-9146532
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91465322022-05-29 Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East Khan, Mohammad Idreesh Ahmad, Md Faruque Ahmad, Irfan Ashfaq, Fauzia Wahab, Shadma Alsayegh, Abdulrahman A. Kumar, Sachil Hakeem, Khalid Rehman Nutrients Review Dietary arsenic (As) contamination is a major public health issue. In the Middle East, the food supply relies primarily on the import of food commodities. Among different age groups the main source of As exposure is grains and grain-based food products, particularly rice and rice-based dietary products. Rice and rice products are a rich source of core macronutrients and act as a chief energy source across the world. The rate of rice consumption ranges from 250 to 650 g per day per person in South East Asian countries. The source of carbohydrates through rice is one of the leading causes of human As exposure. The Gulf population consumes primarily rice and ready-to-eat cereals as a large proportion of their meals. Exposure to arsenic leads to an increased risk of non-communicable diseases such as dysbiosis, obesity, metabolic syndrome, diabetes, chronic kidney disease, chronic heart disease, cancer, and maternal and fetal complications. The impact of arsenic-containing food items and their exposure on health outcomes are different among different age groups. In the Middle East countries, neurological deficit disorder (NDD) and autism spectrum disorder (ASD) cases are alarming issues. Arsenic exposure might be a causative factor that should be assessed by screening the population and regulatory bodies rechecking the limits of As among all age groups. Our goals for this review are to outline the source and distribution of arsenic in various foods and water and summarize the health complications linked with arsenic toxicity along with identified modifiers that add heterogeneity in biological responses and suggest improvements for multi-disciplinary interventions to minimize the global influence of arsenic. The development and validation of diverse analytical techniques to evaluate the toxic levels of different As contaminants in our food products is the need of the hour. Furthermore, standard parameters and guidelines for As-containing foods should be developed and implemented. MDPI 2022-05-20 /pmc/articles/PMC9146532/ /pubmed/35631276 http://dx.doi.org/10.3390/nu14102136 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Khan, Mohammad Idreesh
Ahmad, Md Faruque
Ahmad, Irfan
Ashfaq, Fauzia
Wahab, Shadma
Alsayegh, Abdulrahman A.
Kumar, Sachil
Hakeem, Khalid Rehman
Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title_full Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title_fullStr Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title_full_unstemmed Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title_short Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East
title_sort arsenic exposure through dietary intake and associated health hazards in the middle east
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146532/
https://www.ncbi.nlm.nih.gov/pubmed/35631276
http://dx.doi.org/10.3390/nu14102136
work_keys_str_mv AT khanmohammadidreesh arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT ahmadmdfaruque arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT ahmadirfan arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT ashfaqfauzia arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT wahabshadma arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT alsayeghabdulrahmana arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT kumarsachil arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast
AT hakeemkhalidrehman arsenicexposurethroughdietaryintakeandassociatedhealthhazardsinthemiddleeast