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Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches

Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens and play an important role in the growth-promoting activities of oncoproteins. Truncated LT promotes tumorigenicity as well as h...

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Detalles Bibliográficos
Autores principales: Asseri, Amer H., Alam, Md. Jahidul, Alzahrani, Faisal, Khames, Ahmed, Pathan, Mohammad Turhan, Abourehab, Mohammed A. S., Hosawi, Salman, Ahmed, Rubaiat, Sultana, Sifat Ara, Alam, Nazia Fairooz, Alam, Nafee-Ul, Alam, Rahat, Samad, Abdus, Pokhrel, Sushil, Kim, Jin Kyu, Ahammad, Foysal, Kim, Bonglee, Tan, Shing Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146542/
https://www.ncbi.nlm.nih.gov/pubmed/35631328
http://dx.doi.org/10.3390/ph15050501