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Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches
Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens and play an important role in the growth-promoting activities of oncoproteins. Truncated LT promotes tumorigenicity as well as h...
Autores principales: | Asseri, Amer H., Alam, Md. Jahidul, Alzahrani, Faisal, Khames, Ahmed, Pathan, Mohammad Turhan, Abourehab, Mohammed A. S., Hosawi, Salman, Ahmed, Rubaiat, Sultana, Sifat Ara, Alam, Nazia Fairooz, Alam, Nafee-Ul, Alam, Rahat, Samad, Abdus, Pokhrel, Sushil, Kim, Jin Kyu, Ahammad, Foysal, Kim, Bonglee, Tan, Shing Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146542/ https://www.ncbi.nlm.nih.gov/pubmed/35631328 http://dx.doi.org/10.3390/ph15050501 |
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