Cargando…
HLA-B*57:01 Complexed to a CD8 T-Cell Epitope from the HSV-2 ICP22 Protein Binds NK and T Cells through KIR3DL1
HLA-B*57:01 is an HLA allelic variant associated with positive outcomes during viral infections through interactions with T cells and NK cells, but severe disease in persons treated with the anti-HIV-1 drug abacavir. The role of HLA-B*57:01 in the context of HSV infection is unknown. We identified a...
Autores principales: | Laing, Kerry J., Campbell, Victoria L., Dong, Lichun, Koelle, David M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146709/ https://www.ncbi.nlm.nih.gov/pubmed/35632760 http://dx.doi.org/10.3390/v14051019 |
Ejemplares similares
-
Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01
por: Salzberger, Wilhelm, et al.
Publicado: (2015) -
Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3
por: Moesta, Achim K., et al.
Publicado: (2012) -
HLA Class I and II alleles, heterozygosity and HLA-KIR interactions are associated with rates of genital HSV shedding and lesions
por: Magaret, Amalia, et al.
Publicado: (2016) -
HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2(+) NK cells in Lassa virus infection
por: Wauquier, Nadia, et al.
Publicado: (2019) -
KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells
por: Sim, Malcolm J. W., et al.
Publicado: (2015)