Cargando…
Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber
Controllably accumulating and delivering nanoparticles (NPs) into specific locations are a central theme of nano-engineering and important for targeted therapy or bacteria removal. Here we present a technique allowing bidirectional accumulation, directional delivery and release of nanoparticles thro...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146747/ https://www.ncbi.nlm.nih.gov/pubmed/35630790 http://dx.doi.org/10.3390/molecules27103312 |
_version_ | 1784716638846713856 |
---|---|
author | Wen, Mingcong Yao, Benjun Yuan, Shun Lei, Hongxiang |
author_facet | Wen, Mingcong Yao, Benjun Yuan, Shun Lei, Hongxiang |
author_sort | Wen, Mingcong |
collection | PubMed |
description | Controllably accumulating and delivering nanoparticles (NPs) into specific locations are a central theme of nano-engineering and important for targeted therapy or bacteria removal. Here we present a technique allowing bidirectional accumulation, directional delivery and release of nanoparticles through two 980-nm-wavelength counter-propagating evanescent waves in an optical nanofiber (NF). Using 713-nm-diameter polystyrene NPs suspension and an 890-nm-diameter NF as an example, we experimentally and theoretically demonstrate that the NPs delivered along the NF surface in opposite directions are accumulated into the region where the scattering loss of the NPs is maximum, and about 90% of the incident optical field from both ends of the NF can be coupled into the region. Moreover, the accumulation region can be controlled by altering the incident optical power ratio of the two counter-propagating laser beams, while the accumulated NPs can be delivered and then released into the specific locations by turning off the two lasers. |
format | Online Article Text |
id | pubmed-9146747 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91467472022-05-29 Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber Wen, Mingcong Yao, Benjun Yuan, Shun Lei, Hongxiang Molecules Communication Controllably accumulating and delivering nanoparticles (NPs) into specific locations are a central theme of nano-engineering and important for targeted therapy or bacteria removal. Here we present a technique allowing bidirectional accumulation, directional delivery and release of nanoparticles through two 980-nm-wavelength counter-propagating evanescent waves in an optical nanofiber (NF). Using 713-nm-diameter polystyrene NPs suspension and an 890-nm-diameter NF as an example, we experimentally and theoretically demonstrate that the NPs delivered along the NF surface in opposite directions are accumulated into the region where the scattering loss of the NPs is maximum, and about 90% of the incident optical field from both ends of the NF can be coupled into the region. Moreover, the accumulation region can be controlled by altering the incident optical power ratio of the two counter-propagating laser beams, while the accumulated NPs can be delivered and then released into the specific locations by turning off the two lasers. MDPI 2022-05-21 /pmc/articles/PMC9146747/ /pubmed/35630790 http://dx.doi.org/10.3390/molecules27103312 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Wen, Mingcong Yao, Benjun Yuan, Shun Lei, Hongxiang Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title | Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title_full | Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title_fullStr | Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title_full_unstemmed | Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title_short | Accumulation, Directional Delivery and Release of Nanoparticles along a Nanofiber |
title_sort | accumulation, directional delivery and release of nanoparticles along a nanofiber |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146747/ https://www.ncbi.nlm.nih.gov/pubmed/35630790 http://dx.doi.org/10.3390/molecules27103312 |
work_keys_str_mv | AT wenmingcong accumulationdirectionaldeliveryandreleaseofnanoparticlesalongananofiber AT yaobenjun accumulationdirectionaldeliveryandreleaseofnanoparticlesalongananofiber AT yuanshun accumulationdirectionaldeliveryandreleaseofnanoparticlesalongananofiber AT leihongxiang accumulationdirectionaldeliveryandreleaseofnanoparticlesalongananofiber |