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The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center

Information about the impact of SARS-CoV-2 infection on pregnant women is still limited and raises challenges, even as publications are increasing rapidly. The aim of the present study was to determine the impact of SARS-CoV-2 infection on preterm birth pregnancies. We performed a prospective, obser...

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Autores principales: Bobei, Tina-Ioana, Haj Hamoud, Bashar, Sima, Romina-Marina, Gorecki, Gabriel-Petre, Poenaru, Mircea-Octavian, Olaru, Octavian-Gabriel, Ples, Liana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146843/
https://www.ncbi.nlm.nih.gov/pubmed/35630005
http://dx.doi.org/10.3390/medicina58050587
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author Bobei, Tina-Ioana
Haj Hamoud, Bashar
Sima, Romina-Marina
Gorecki, Gabriel-Petre
Poenaru, Mircea-Octavian
Olaru, Octavian-Gabriel
Ples, Liana
author_facet Bobei, Tina-Ioana
Haj Hamoud, Bashar
Sima, Romina-Marina
Gorecki, Gabriel-Petre
Poenaru, Mircea-Octavian
Olaru, Octavian-Gabriel
Ples, Liana
author_sort Bobei, Tina-Ioana
collection PubMed
description Information about the impact of SARS-CoV-2 infection on pregnant women is still limited and raises challenges, even as publications are increasing rapidly. The aim of the present study was to determine the impact of SARS-CoV-2 infection on preterm birth pregnancies. We performed a prospective, observational study in a COVID-only hospital, which included 34 pregnant women with SARS-CoV-2 infection and preterm birth compared with a control group of 48 healthy women with preterm birth. The rate of cesarean delivery was 82% in the study group versus 6% for the control group. We observed a strong correlation between premature birth and the presence of COVID-19 symptoms (cough p = 0.029, fever p = 0.001, and chills p = 0.001). The risk for premature birth is correlated to a lower value of oxygen saturation (p = 0.001) and extensive radiologic pulmonary lesions (p = 0.025). The COVID-19 pregnant women with preterm delivery were older, and experienced an exacerbation of severe respiratory symptoms, decreased saturation of oxygen, increased inflammatory markers, severe pulmonary lesions and decreased lymphocytes.
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spelling pubmed-91468432022-05-29 The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center Bobei, Tina-Ioana Haj Hamoud, Bashar Sima, Romina-Marina Gorecki, Gabriel-Petre Poenaru, Mircea-Octavian Olaru, Octavian-Gabriel Ples, Liana Medicina (Kaunas) Article Information about the impact of SARS-CoV-2 infection on pregnant women is still limited and raises challenges, even as publications are increasing rapidly. The aim of the present study was to determine the impact of SARS-CoV-2 infection on preterm birth pregnancies. We performed a prospective, observational study in a COVID-only hospital, which included 34 pregnant women with SARS-CoV-2 infection and preterm birth compared with a control group of 48 healthy women with preterm birth. The rate of cesarean delivery was 82% in the study group versus 6% for the control group. We observed a strong correlation between premature birth and the presence of COVID-19 symptoms (cough p = 0.029, fever p = 0.001, and chills p = 0.001). The risk for premature birth is correlated to a lower value of oxygen saturation (p = 0.001) and extensive radiologic pulmonary lesions (p = 0.025). The COVID-19 pregnant women with preterm delivery were older, and experienced an exacerbation of severe respiratory symptoms, decreased saturation of oxygen, increased inflammatory markers, severe pulmonary lesions and decreased lymphocytes. MDPI 2022-04-25 /pmc/articles/PMC9146843/ /pubmed/35630005 http://dx.doi.org/10.3390/medicina58050587 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bobei, Tina-Ioana
Haj Hamoud, Bashar
Sima, Romina-Marina
Gorecki, Gabriel-Petre
Poenaru, Mircea-Octavian
Olaru, Octavian-Gabriel
Ples, Liana
The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title_full The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title_fullStr The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title_full_unstemmed The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title_short The Impact of SARS-CoV-2 Infection on Premature Birth—Our Experience as COVID Center
title_sort impact of sars-cov-2 infection on premature birth—our experience as covid center
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146843/
https://www.ncbi.nlm.nih.gov/pubmed/35630005
http://dx.doi.org/10.3390/medicina58050587
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