Arene Ru(II) Complexes Acted as Potential KRAS G-Quadruplex DNA Stabilizer Induced DNA Damage Mediated Apoptosis to Inhibit Breast Cancer Progress

A series of arene Ru(II) complexes, [(η(6)-MeC(6)H(5))Ru(L)Cl]Cl, (L=o-ClPIP, 1; m-ClPIP, 2 and p-ClPIP, 3) (o-ClPIP=2-(2-chlorophenyl)imidazo[4,5-f][1,10]phenanthroline; m-ClPIP=2-(3-chlorophenyl)imidazo[4,5-f][1,10]phenanthroline; p-ClPIP=2-(4-chlorophenyl)imidazo[4,5-f][1,10]phenanthroline) was s...

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Detalles Bibliográficos
Autores principales: Qian, Jiayi, Liu, Ruotong, Liu, Ningzhi, Yuan, Chanling, Wu, Qiong, Chen, Yanhua, Tan, Weijun, Mei, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146995/
https://www.ncbi.nlm.nih.gov/pubmed/35630522
http://dx.doi.org/10.3390/molecules27103046

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