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Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents

Ken Breslauer began studies on the thermodynamics of small cationic molecules binding in the DNA minor groove over 30 years ago, and the studies reported here are an extension of those ground-breaking reports. The goals of this report are to develop a detailed understanding of the binding thermodyna...

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Detalles Bibliográficos
Autores principales:	Paul, Ananya, Farahat, Abdelbasset A., Boykin, David W., Wilson, W. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147024/ https://www.ncbi.nlm.nih.gov/pubmed/35629349 http://dx.doi.org/10.3390/life12050681

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