Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants

Cytochrome P450 (CYP) enzymes, such as CYP3A4, and CYP3A5, P450 oxidoreductase (POR), peroxisome proliferator activated receptor alpha (PPAR-alpha), and drug transporter (ABCB1) were observed to influence concentrations of immunosuppressants (cyclosporine, everolimus, sirolimus, and tacrolimus) and...

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Detalles Bibliográficos
Autores principales: Sridharan, Kannan, Shah, Shamik, Jassim, Anfal, Hammad, Mona, Ebrahim Al Gadhban, Johaina, Al Segai, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147030/
https://www.ncbi.nlm.nih.gov/pubmed/35629245
http://dx.doi.org/10.3390/jpm12050823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147030/
https://www.ncbi.nlm.nih.gov/pubmed/35629245
http://dx.doi.org/10.3390/jpm12050823

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