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Fast In Vitro Release and In Vivo Absorption of an Anti-Schizophrenic Drug Paliperidone from Its Soluplus(®)/TPGS Mixed Micelles
The purpose of this study was to develop a drug delivery system for paliperidone (PPD) in order to provide a more effective therapeutic strategy for patients with acute schizophrenia. PPD-loaded Soluplus(®)/TPGS mixed micelles (PPD-S/T-MM) were prepared using the thin-film hydration method. The crit...
Autores principales: | Zhou, Ye, Wang, Chenhui, Liu, Wenqian, Yang, Meiqing, Xu, Bohui, Chen, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147083/ https://www.ncbi.nlm.nih.gov/pubmed/35631475 http://dx.doi.org/10.3390/pharmaceutics14050889 |
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