CRISPR/Cas9 Editing of Duck Enteritis Virus Genome for the Construction of a Recombinant Vaccine Vector Expressing ompH Gene of Pasteurella multocida in Two Novel Insertion Sites

Duck enteritis virus (DEV) and Pasteurella multocida, the causative agent of duck plague and fowl cholera, are acute contagious diseases and leading causes of morbidity and mortality in duck. The NHEJ-CRISPR/Cas9-mediated gene editing strategy, accompanied with the Cre–Lox system, have been employed...

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Detalles Bibliográficos
Autores principales: Apinda, Nisachon, Yao, Yongxiu, Zhang, Yaoyao, Reddy, Vishwanatha R. A. P., Chang, Pengxiang, Nair, Venugopal, Sthitmatee, Nattawooti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147145/
https://www.ncbi.nlm.nih.gov/pubmed/35632442
http://dx.doi.org/10.3390/vaccines10050686

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