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Probing the Mechanism of Action of Cry41Aa on HepG2 through the Establishment of a Resistant Subline
Cry41Aa, also called parasporin-3, belongs to a group of toxins from the entomopathogenic bacterium Bacillus thuringiensis that show activity against human cancer cells. Cry41Aa exhibits preferential cytocidal activity towards HL-60 (human promyelocytic leukaemia cells) and HepG2 (human liver cancer...
Autores principales: | Souissi, Wided, Alistair, Tweedie, Domanska, Barbara, Fortea, Eva, West, Michelle J., Schwartz, Jean-Louis, Crickmore, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147150/ https://www.ncbi.nlm.nih.gov/pubmed/35622566 http://dx.doi.org/10.3390/toxins14050319 |
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