Evaluation of the Anti-Histoplasma capsulatum Activity of Indole and Nitrofuran Derivatives and Their Pharmacological Safety in Three-Dimensional Cell Cultures

Histoplasma capsulatum is a fungus that causes histoplasmosis. The increased evolution of microbial resistance and the adverse effects of current antifungals help new drugs to emerge. In this work, fifty-four nitrofurans and indoles were tested against the H. capsulatum EH-315 strain. Compounds with...

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Detalles Bibliográficos
Autores principales: Vaso, Carolina Orlando, Bila, Níura Madalena, Pandolfi, Fabiana, De Vita, Daniela, Bortolami, Martina, Bonatti, Jean Lucas Carvalho, de Moraes Silva, Rosângela Aparecida, Gonçalves, Larissa Naiara Carvalho, Tudino, Valeria, Costi, Roberta, Di Santo, Roberto, Mendes-Giannini, Maria José Soares, Costa-Orlandi, Caroline Barcelos, Scipione, Luigi, Fusco-Almeida, Ana Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147190/
https://www.ncbi.nlm.nih.gov/pubmed/35631629
http://dx.doi.org/10.3390/pharmaceutics14051043

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