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A Hot-Melt Extrusion Risk Assessment Classification System for Amorphous Solid Dispersion Formulation Development

Several literature publications have described the potential application of active pharmaceutical ingredient (API)–polymer phase diagrams to identify appropriate temperature ranges for processing amorphous solid dispersion (ASD) formulations via the hot-melt extrusion (HME) technique. However, syste...

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Detalles Bibliográficos
Autores principales: Kyeremateng, Samuel O., Voges, Kristin, Dohrn, Stefanie, Sobich, Ekaterina, Lander, Ute, Weber, Stefan, Gessner, David, Evans, Rachel C., Degenhardt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147278/
https://www.ncbi.nlm.nih.gov/pubmed/35631630
http://dx.doi.org/10.3390/pharmaceutics14051044