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Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection
Measles is an RNA virus infectious disease mainly seen in children. Despite the availability of an effective vaccine against measles, it remains a health issue in children. Although it is a self-limiting disease, it becomes severe in undernourished and immune-compromised individuals. Measles infecti...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147347/ https://www.ncbi.nlm.nih.gov/pubmed/35630096 http://dx.doi.org/10.3390/medicina58050680 |
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author | Rabaan, Ali A. Mutair, Abbas Al Alhumaid, Saad Garout, Mohammed Alsubki, Roua A. Alshahrani, Fatimah S. Alfouzan, Wadha A. Alestad, Jeehan H. Alsaleh, Abdullah E. Al-Mozaini, Maha A. Koritala, Thoyaja Alotaibi, Sultan Temsah, Mohamad-Hani Akbar, Ali Ahmad, Rafiq Khalid, Zainab Muhammad, Javed Ahmed, Naveed |
author_facet | Rabaan, Ali A. Mutair, Abbas Al Alhumaid, Saad Garout, Mohammed Alsubki, Roua A. Alshahrani, Fatimah S. Alfouzan, Wadha A. Alestad, Jeehan H. Alsaleh, Abdullah E. Al-Mozaini, Maha A. Koritala, Thoyaja Alotaibi, Sultan Temsah, Mohamad-Hani Akbar, Ali Ahmad, Rafiq Khalid, Zainab Muhammad, Javed Ahmed, Naveed |
author_sort | Rabaan, Ali A. |
collection | PubMed |
description | Measles is an RNA virus infectious disease mainly seen in children. Despite the availability of an effective vaccine against measles, it remains a health issue in children. Although it is a self-limiting disease, it becomes severe in undernourished and immune-compromised individuals. Measles infection is associated with secondary infections by opportunistic bacteria due to the immunosuppressive effects of the measles virus. Recent reports highlight that measles infection erases the already existing immune memory of various pathogens. This review covers the incidence, pathogenesis, measles variants, clinical presentations, secondary infections, elimination of measles virus on a global scale, and especially the immune responses related to measles infection. |
format | Online Article Text |
id | pubmed-9147347 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91473472022-05-29 Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection Rabaan, Ali A. Mutair, Abbas Al Alhumaid, Saad Garout, Mohammed Alsubki, Roua A. Alshahrani, Fatimah S. Alfouzan, Wadha A. Alestad, Jeehan H. Alsaleh, Abdullah E. Al-Mozaini, Maha A. Koritala, Thoyaja Alotaibi, Sultan Temsah, Mohamad-Hani Akbar, Ali Ahmad, Rafiq Khalid, Zainab Muhammad, Javed Ahmed, Naveed Medicina (Kaunas) Review Measles is an RNA virus infectious disease mainly seen in children. Despite the availability of an effective vaccine against measles, it remains a health issue in children. Although it is a self-limiting disease, it becomes severe in undernourished and immune-compromised individuals. Measles infection is associated with secondary infections by opportunistic bacteria due to the immunosuppressive effects of the measles virus. Recent reports highlight that measles infection erases the already existing immune memory of various pathogens. This review covers the incidence, pathogenesis, measles variants, clinical presentations, secondary infections, elimination of measles virus on a global scale, and especially the immune responses related to measles infection. MDPI 2022-05-20 /pmc/articles/PMC9147347/ /pubmed/35630096 http://dx.doi.org/10.3390/medicina58050680 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Rabaan, Ali A. Mutair, Abbas Al Alhumaid, Saad Garout, Mohammed Alsubki, Roua A. Alshahrani, Fatimah S. Alfouzan, Wadha A. Alestad, Jeehan H. Alsaleh, Abdullah E. Al-Mozaini, Maha A. Koritala, Thoyaja Alotaibi, Sultan Temsah, Mohamad-Hani Akbar, Ali Ahmad, Rafiq Khalid, Zainab Muhammad, Javed Ahmed, Naveed Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title | Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title_full | Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title_fullStr | Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title_full_unstemmed | Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title_short | Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection |
title_sort | updates on measles incidence and eradication: emphasis on the immunological aspects of measles infection |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147347/ https://www.ncbi.nlm.nih.gov/pubmed/35630096 http://dx.doi.org/10.3390/medicina58050680 |
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