Gold Ion Beam Milled Gold Zero-Mode Waveguides

Zero-mode waveguides (ZMWs) are widely used in single molecule fluorescence microscopy for their enhancement of emitted light and the ability to study samples at physiological concentrations. ZMWs are typically produced using photo or electron beam lithography. We report a new method of ZMW producti...

Descripción completa

Detalles Bibliográficos
Autores principales: Messina, Troy C., Srijanto, Bernadeta R., Collier, Charles Patrick, Kravchenko, Ivan I., Richards, Christopher I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147361/
https://www.ncbi.nlm.nih.gov/pubmed/35630978
http://dx.doi.org/10.3390/nano12101755
_version_ 1784716788861239296
author Messina, Troy C.
Srijanto, Bernadeta R.
Collier, Charles Patrick
Kravchenko, Ivan I.
Richards, Christopher I.
author_facet Messina, Troy C.
Srijanto, Bernadeta R.
Collier, Charles Patrick
Kravchenko, Ivan I.
Richards, Christopher I.
author_sort Messina, Troy C.
collection PubMed
description Zero-mode waveguides (ZMWs) are widely used in single molecule fluorescence microscopy for their enhancement of emitted light and the ability to study samples at physiological concentrations. ZMWs are typically produced using photo or electron beam lithography. We report a new method of ZMW production using focused ion beam (FIB) milling with gold ions. We demonstrate that ion-milled gold ZMWs with 200 nm apertures exhibit similar plasmon-enhanced fluorescence seen with ZMWs fabricated with traditional techniques such as electron beam lithography.
format Online
Article
Text
id pubmed-9147361
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91473612022-05-29 Gold Ion Beam Milled Gold Zero-Mode Waveguides Messina, Troy C. Srijanto, Bernadeta R. Collier, Charles Patrick Kravchenko, Ivan I. Richards, Christopher I. Nanomaterials (Basel) Article Zero-mode waveguides (ZMWs) are widely used in single molecule fluorescence microscopy for their enhancement of emitted light and the ability to study samples at physiological concentrations. ZMWs are typically produced using photo or electron beam lithography. We report a new method of ZMW production using focused ion beam (FIB) milling with gold ions. We demonstrate that ion-milled gold ZMWs with 200 nm apertures exhibit similar plasmon-enhanced fluorescence seen with ZMWs fabricated with traditional techniques such as electron beam lithography. MDPI 2022-05-21 /pmc/articles/PMC9147361/ /pubmed/35630978 http://dx.doi.org/10.3390/nano12101755 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Messina, Troy C.
Srijanto, Bernadeta R.
Collier, Charles Patrick
Kravchenko, Ivan I.
Richards, Christopher I.
Gold Ion Beam Milled Gold Zero-Mode Waveguides
title Gold Ion Beam Milled Gold Zero-Mode Waveguides
title_full Gold Ion Beam Milled Gold Zero-Mode Waveguides
title_fullStr Gold Ion Beam Milled Gold Zero-Mode Waveguides
title_full_unstemmed Gold Ion Beam Milled Gold Zero-Mode Waveguides
title_short Gold Ion Beam Milled Gold Zero-Mode Waveguides
title_sort gold ion beam milled gold zero-mode waveguides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147361/
https://www.ncbi.nlm.nih.gov/pubmed/35630978
http://dx.doi.org/10.3390/nano12101755
work_keys_str_mv AT messinatroyc goldionbeammilledgoldzeromodewaveguides
AT srijantobernadetar goldionbeammilledgoldzeromodewaveguides
AT colliercharlespatrick goldionbeammilledgoldzeromodewaveguides
AT kravchenkoivani goldionbeammilledgoldzeromodewaveguides
AT richardschristopheri goldionbeammilledgoldzeromodewaveguides

Ejemplares similares