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Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective

To improve patient outcomes after trauma, the need to decrypt the post-traumatic immune response has been identified. One prerequisite to drive advancement in understanding that domain is the implementation of surgical biobanks. This paper focuses on the outcomes of patients with one of two diagnose...

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Autores principales: Brochhausen, Mathias, Whorton, Justin M., Zayas, Cilia E., Kimbrell, Monica P., Bost, Sarah J., Singh, Nitya, Brochhausen, Christoph, Sexton, Kevin W., Blobel, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147545/
https://www.ncbi.nlm.nih.gov/pubmed/35629179
http://dx.doi.org/10.3390/jpm12050757
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author Brochhausen, Mathias
Whorton, Justin M.
Zayas, Cilia E.
Kimbrell, Monica P.
Bost, Sarah J.
Singh, Nitya
Brochhausen, Christoph
Sexton, Kevin W.
Blobel, Bernd
author_facet Brochhausen, Mathias
Whorton, Justin M.
Zayas, Cilia E.
Kimbrell, Monica P.
Bost, Sarah J.
Singh, Nitya
Brochhausen, Christoph
Sexton, Kevin W.
Blobel, Bernd
author_sort Brochhausen, Mathias
collection PubMed
description To improve patient outcomes after trauma, the need to decrypt the post-traumatic immune response has been identified. One prerequisite to drive advancement in understanding that domain is the implementation of surgical biobanks. This paper focuses on the outcomes of patients with one of two diagnoses: post-traumatic arthritis and osteomyelitis. In creating surgical biobanks, currently, many obstacles must be overcome. Roadblocks exist around scoping of data that is to be collected, and the semantic integration of these data. In this paper, the generic component model and the Semantic Web technology stack are used to solve issues related to data integration. The results are twofold: (a) a scoping analysis of data and the ontologies required to harmonize and integrate it, and (b) resolution of common data integration issues in integrating data relevant to trauma surgery.
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spelling pubmed-91475452022-05-29 Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective Brochhausen, Mathias Whorton, Justin M. Zayas, Cilia E. Kimbrell, Monica P. Bost, Sarah J. Singh, Nitya Brochhausen, Christoph Sexton, Kevin W. Blobel, Bernd J Pers Med Article To improve patient outcomes after trauma, the need to decrypt the post-traumatic immune response has been identified. One prerequisite to drive advancement in understanding that domain is the implementation of surgical biobanks. This paper focuses on the outcomes of patients with one of two diagnoses: post-traumatic arthritis and osteomyelitis. In creating surgical biobanks, currently, many obstacles must be overcome. Roadblocks exist around scoping of data that is to be collected, and the semantic integration of these data. In this paper, the generic component model and the Semantic Web technology stack are used to solve issues related to data integration. The results are twofold: (a) a scoping analysis of data and the ontologies required to harmonize and integrate it, and (b) resolution of common data integration issues in integrating data relevant to trauma surgery. MDPI 2022-05-07 /pmc/articles/PMC9147545/ /pubmed/35629179 http://dx.doi.org/10.3390/jpm12050757 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Brochhausen, Mathias
Whorton, Justin M.
Zayas, Cilia E.
Kimbrell, Monica P.
Bost, Sarah J.
Singh, Nitya
Brochhausen, Christoph
Sexton, Kevin W.
Blobel, Bernd
Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title_full Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title_fullStr Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title_full_unstemmed Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title_short Assessing the Need for Semantic Data Integration for Surgical Biobanks—A Knowledge Representation Perspective
title_sort assessing the need for semantic data integration for surgical biobanks—a knowledge representation perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147545/
https://www.ncbi.nlm.nih.gov/pubmed/35629179
http://dx.doi.org/10.3390/jpm12050757
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