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Delayed Ventricular Repolarization and Sodium Channel Current Modification in a Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a severe developmental disorder that is strongly linked to mutations in the MECP2 gene. RTT has been associated with sudden unexplained death and ECG QT interval prolongation. There are mixed reports regarding QT prolongation in mouse models of RTT, with some evidence that los...

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Detalles Bibliográficos
Autores principales: Cheng, Hongwei, Charles, Ian, James, Andrew F., Abdala, Ana P., Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147596/
https://www.ncbi.nlm.nih.gov/pubmed/35628543
http://dx.doi.org/10.3390/ijms23105735

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