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Pleiotrophin Interaction with Synthetic Glycosaminoglycan Mimetics

Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo. Some structures of PTN in solution have been solved, but no precise location of the binding site has been reported yet. Using (15)N-labelled PTN and HSQC NMR experiments, we stu...

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Detalles Bibliográficos
Autores principales: Miles, Jonathan R., Wang, Xu, de Paz, Jose L., Nieto, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147657/
https://www.ncbi.nlm.nih.gov/pubmed/35631323
http://dx.doi.org/10.3390/ph15050496

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