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Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors

Foods rich in antioxidants such as lycopene have a major role in maintaining cardiac health. Lycopene, 80% of which can be obtained by consuming a common vegetable such as tomato, can prevent the disturbances that contribute to cardiovascular disease (CVD). The present work begins with a brief intro...

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Detalles Bibliográficos
Autores principales: Hsieh, Ming-Ju, Huang, Chih-Yang, Kiefer, Rudolf, Lee, Shin-Da, Maurya, Nancy, Velmurugan, Bharath Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147660/
https://www.ncbi.nlm.nih.gov/pubmed/35630709
http://dx.doi.org/10.3390/molecules27103235
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author Hsieh, Ming-Ju
Huang, Chih-Yang
Kiefer, Rudolf
Lee, Shin-Da
Maurya, Nancy
Velmurugan, Bharath Kumar
author_facet Hsieh, Ming-Ju
Huang, Chih-Yang
Kiefer, Rudolf
Lee, Shin-Da
Maurya, Nancy
Velmurugan, Bharath Kumar
author_sort Hsieh, Ming-Ju
collection PubMed
description Foods rich in antioxidants such as lycopene have a major role in maintaining cardiac health. Lycopene, 80% of which can be obtained by consuming a common vegetable such as tomato, can prevent the disturbances that contribute to cardiovascular disease (CVD). The present work begins with a brief introduction to CVD and lycopene and its various properties such as bioavailability, pharmacokinetics, etc. In this review, the potential cardio-protective effects of lycopene that reduce the progression of CVD and thrombotic complications are detailed. Further, the protective effects of lycopene including in vitro, in vivo and clinical trials conducted on lycopene for CVD protective effects are explained. Finally, the controversial aspect of lycopene as a protective agent against CVD and toxicity are also mentioned.
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spelling pubmed-91476602022-05-29 Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors Hsieh, Ming-Ju Huang, Chih-Yang Kiefer, Rudolf Lee, Shin-Da Maurya, Nancy Velmurugan, Bharath Kumar Molecules Review Foods rich in antioxidants such as lycopene have a major role in maintaining cardiac health. Lycopene, 80% of which can be obtained by consuming a common vegetable such as tomato, can prevent the disturbances that contribute to cardiovascular disease (CVD). The present work begins with a brief introduction to CVD and lycopene and its various properties such as bioavailability, pharmacokinetics, etc. In this review, the potential cardio-protective effects of lycopene that reduce the progression of CVD and thrombotic complications are detailed. Further, the protective effects of lycopene including in vitro, in vivo and clinical trials conducted on lycopene for CVD protective effects are explained. Finally, the controversial aspect of lycopene as a protective agent against CVD and toxicity are also mentioned. MDPI 2022-05-18 /pmc/articles/PMC9147660/ /pubmed/35630709 http://dx.doi.org/10.3390/molecules27103235 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hsieh, Ming-Ju
Huang, Chih-Yang
Kiefer, Rudolf
Lee, Shin-Da
Maurya, Nancy
Velmurugan, Bharath Kumar
Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title_full Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title_fullStr Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title_full_unstemmed Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title_short Cardiovascular Disease and Possible Ways in Which Lycopene Acts as an Efficient Cardio-Protectant against Different Cardiovascular Risk Factors
title_sort cardiovascular disease and possible ways in which lycopene acts as an efficient cardio-protectant against different cardiovascular risk factors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147660/
https://www.ncbi.nlm.nih.gov/pubmed/35630709
http://dx.doi.org/10.3390/molecules27103235
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