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Membrane Cholesterol Content and Lipid Organization Influence Melittin and Pneumolysin Pore-Forming Activity

Melittin, the main toxic component in the venom of the European honeybee, interacts with natural and artificial membranes due to its amphiphilic properties. Rather than interacting with a specific receptor, melittin interacts with the lipid components, disrupting the lipid bilayer and inducing ion l...

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Detalles Bibliográficos
Autores principales: Ganpule, Shamish, Vijaya, Akshay Kumar, Sukova, Aleksandra, Preta, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147762/
https://www.ncbi.nlm.nih.gov/pubmed/35622592
http://dx.doi.org/10.3390/toxins14050346

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