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Membrane Cholesterol Content and Lipid Organization Influence Melittin and Pneumolysin Pore-Forming Activity
Melittin, the main toxic component in the venom of the European honeybee, interacts with natural and artificial membranes due to its amphiphilic properties. Rather than interacting with a specific receptor, melittin interacts with the lipid components, disrupting the lipid bilayer and inducing ion l...
Autores principales: | Ganpule, Shamish, Vijaya, Akshay Kumar, Sukova, Aleksandra, Preta, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147762/ https://www.ncbi.nlm.nih.gov/pubmed/35622592 http://dx.doi.org/10.3390/toxins14050346 |
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