Cargando…

Activity of a Carbohydrate-Binding Module Therapy, Neumifil, against SARS-CoV-2 Disease in a Hamster Model of Infection

The rapid global spread of severe acute respiratory coronavirus 2 (SARS-CoV-2) has resulted in an urgent effort to find efficacious therapeutics. Broad-spectrum therapies which could be used for other respiratory pathogens confer advantages, as do those based on targeting host cells that are not pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fell, Rachel, Potter, Jane A., Yuille, Samantha, Salguero, Franscisco J., Watson, Robert, Ngabo, Didier, Gooch, Karen, Hewson, Roger, Howat, David, Dowall, Stuart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147764/ https://www.ncbi.nlm.nih.gov/pubmed/35632718 http://dx.doi.org/10.3390/v14050976

Ejemplares similares

Use of a Preclinical Natural Transmission Model to Study Antiviral Effects of a Carbohydrate-Binding Module Therapy against SARS-CoV-2 in Hamsters
por: Knott, Daniel, et al.
Publicado: (2023)

Development of a Hamster Natural Transmission Model of SARS-CoV-2 Infection
por: Dowall, Stuart, et al.
Publicado: (2021)

SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum
por: Handley, Alastair, et al.
Publicado: (2023)

Establishment of a Nipah Virus Disease Model in Hamsters, including a Comparison of Intranasal and Intraperitoneal Routes of Challenge
por: Findlay-Wilson, Stephen, et al.
Publicado: (2023)

Hantavirus infection in type I interferon receptor-deficient (A129) mice
por: Dowall, Stuart D., et al.
Publicado: (2020)

Development of vaccines against Crimean-Congo haemorrhagic fever virus
por: Dowall, Stuart D., et al.
Publicado: (2017)

Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
por: Ryan, Kathryn A., et al.
Publicado: (2023)

Multiplex cytokine profiling with highly pathogenic material: Use of formalin solution in luminex analysis
por: Dowall, Stuart D., et al.
Publicado: (2009)

A Susceptible Mouse Model for Zika Virus Infection
por: Dowall, Stuart D., et al.
Publicado: (2016)

Effect of cholestyramine on the formation of pigment gallstone in high carbohydrate diet-fed hamsters.
por: Lee, Y. C., et al.
Publicado: (1996)

A Novel Vaccine against Crimean-Congo Haemorrhagic Fever Protects 100% of Animals against Lethal Challenge in a Mouse Model
por: Buttigieg, Karen R., et al.
Publicado: (2014)

The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
por: Davies, Elizabeth R., et al.
Publicado: (2023)

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor
por: Yang, Lei, et al.
Publicado: (2015)

Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses
por: Dowall, Stuart D., et al.
Publicado: (2016)

Emerging viruses and current strategies for vaccine intervention
por: Afrough, B., et al.
Publicado: (2019)

Erratum to: Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor
por: Yang, Lei, et al.
Publicado: (2015)

Complete Genome Sequence of Zika Virus Isolated from Semen
por: Atkinson, Barry, et al.
Publicado: (2016)

THE FINE STRUCTURE OF NORMAL AND NEOPLASTIC MELANOCYTES IN THE SYRIAN HAMSTER, WITH PARTICULAR REFERENCE TO CARCINOGEN-INDUCED MELANOTIC TUMORS
por: Rappaport, Henry, et al.
Publicado: (1963)

Serological and Virological Evidence of Crimean-Congo Haemorrhagic Fever Virus Circulation in the Human Population of Borno State, Northeastern Nigeria
por: Bukbuk, David N., et al.
Publicado: (2016)

Detection of natural cytotoxicity in Syrian hamsters.
por: Rees, R. C., et al.
Publicado: (1980)

Lineage-dependent differences in the disease progression of Zika virus infection in type-I interferon receptor knockout (A129) mice
por: Dowall, Stuart D., et al.
Publicado: (2017)

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19
por: Huo, Jiandong, et al.
Publicado: (2021)

Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins
por: Findlay-Wilson, Stephen, et al.
Publicado: (2022)

Absence of Crimean-Congo haemorrhagic fever virus in the tick Hyalomma aegyptium parasitizing the spur-thighed tortoise (Testudo graeca) in Tunisia
por: Fares, Wasfi, et al.
Publicado: (2019)

Effective Binding of a Phosphatidylserine-Targeting Antibody to Ebola Virus Infected Cells and Purified Virions
por: Dowall, S. D., et al.
Publicado: (2015)

Use of Chinese hamster ovary cells with altered glycosylation patterns to define the carbohydrate specificity of Entamoeba histolytica adhesion
Publicado: (1988)

Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐Binding Lectins
por: Kuhaudomlarp, Sakonwan, et al.
Publicado: (2021)

Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)(2) fragments
por: Findlay-Wilson, Stephen, et al.
Publicado: (2023)

Publisher Correction: Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)(2) fragments
por: Findlay‑Wilson, Stephen, et al.
Publicado: (2023)

X-ray inactivation of RNA viruses without loss of biological characteristics
por: Afrough, Babak, et al.
Publicado: (2020)

Promiscuity of the Euonymus Carbohydrate-Binding Domain
por: Fouquaert, Elke, et al.
Publicado: (2012)

Tyrosyltubulin ligase and colchicine binding activity in synchronized Chinese hamster cells
Publicado: (1978)

Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle
por: Surtees, Rebecca, et al.
Publicado: (2016)

Using Carbohydrate Interaction Assays to Reveal Novel Binding Sites in Carbohydrate Active Enzymes
por: Cockburn, Darrell, et al.
Publicado: (2016)

The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases
por: Iizuka, Katsumi
Publicado: (2021)

Bola‐Amphiphilic Glycodendrimers: New Carbohydrate‐Mimicking Scaffolds to Target Carbohydrate‐Binding Proteins
por: Zhang, Wenzheng, et al.
Publicado: (2022)

A High-Carbohydrate Diet Prolongs Dysbiosis and Clostridioides difficile Carriage and Increases Delayed Mortality in a Hamster Model of Infection
por: Bhute, Shrikant S., et al.
Publicado: (2022)

Tick-Borne Encephalitis Virus, United Kingdom
por: Holding, Maya, et al.
Publicado: (2020)

Investigating the Cellular Transcriptomic Response Induced by the Makona Variant of Ebola Virus in Differentiated THP-1 Cells
por: Bosworth, Andrew, et al.
Publicado: (2019)

Gold nanoparticle-based multivalent carbohydrate probes: selective photoaffinity labeling of carbohydrate-binding proteins
por: Sakurai, Kaori, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6bgjumbfsnb2oq0lmufqdd3jae