Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

YKL-40 (also named chitinase 3 like-1 protein [CHI3L1]) is a secreted chitinase-like protein which is upregulated in cancers and suggested to have pro-tumorigenic activity. YKL-40 lacks enzymatic function, but it can bind carbohydrates such as chitin. Chitooligosaccharides (COS) derived from deacety...

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Detalles Bibliográficos
Autores principales: Johansen, Astrid Zedlitz, Carretta, Marco, Thorseth, Marie-Louise, Khan, Shawez, Fjæstad, Klaire Yixin, Brøchner, Christian Beltoft, Linder, Hannes, Ankjærgaard, Christina, Donia, Marco, Chen, Inna, Nielsen, Dorte Lisbet, Behrens, Claus Preibisch, Madsen, Daniel Hargbøl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147765/
https://www.ncbi.nlm.nih.gov/pubmed/35631632
http://dx.doi.org/10.3390/pharmaceutics14051046

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