Synthesis of Coumarin Derivatives: A New Class of Coumarin-Based G Protein-Coupled Receptor Activators and Inhibitors

To expand the range of daphnetin-based inhibitors/activators used for targeting G protein-coupled receptors (GPCRs) in disease treatment, twenty-five coumarin derivatives 1–25, including 7,8-dihydroxycoumarin and 7-hydroxycoumarin derivatives with various substitution patterns/groups at C3-/4- posit...

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Detalles Bibliográficos
Autores principales: Fu, Zhe, Zhang, Linjie, Hang, Sijin, Wang, Shiyi, Li, Na, Sun, Xiaojing, Wang, Zian, Sheng, Ruilong, Wang, Fang, Wu, Wenhui, Guo, Ruihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147790/
https://www.ncbi.nlm.nih.gov/pubmed/35631901
http://dx.doi.org/10.3390/polym14102021

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