Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies

The enzyme reverse transcriptase (RT) plays a central role in the life cycle of human immunodeficiency virus (HIV), and RT has been an important drug target. Elucidations of the RT structures trapping and detailing the enzyme at various functional and conformational states by X-ray crystallography h...

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Detalles Bibliográficos
Autores principales: Singh, Abhimanyu K., Das, Kalyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148108/
https://www.ncbi.nlm.nih.gov/pubmed/35632767
http://dx.doi.org/10.3390/v14051027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148108/
https://www.ncbi.nlm.nih.gov/pubmed/35632767
http://dx.doi.org/10.3390/v14051027

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