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Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?

We investigated the storage lower urinary tract symptoms (LUTS) before and after the first dose of coronavirus disease 2019 (COVID-19) vaccine and the association between pre-vaccinated overactive bladder (OAB) and the worsening of storage LUTS following COVID-19 vaccination. This cross-sectional st...

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Autores principales: Chen, Yu-Chen, Liang, Yin-Chi, Ho, Shuo-Jung, Chen, Hao-Wei, Juan, Yung-Shun, Tsai, Wei-Chung, Huang, Shu-Pin, Lee, Jung-Ting, Liu, Yu-Peng, Kao, Chung-Yao, Lin, Yen-Ko, Long, Cheng-Yu, Wu, Meng-Ni, Chen, Chao-Ju, Wu, Wen-Jeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148126/
https://www.ncbi.nlm.nih.gov/pubmed/35628863
http://dx.doi.org/10.3390/jcm11102736
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author Chen, Yu-Chen
Liang, Yin-Chi
Ho, Shuo-Jung
Chen, Hao-Wei
Juan, Yung-Shun
Tsai, Wei-Chung
Huang, Shu-Pin
Lee, Jung-Ting
Liu, Yu-Peng
Kao, Chung-Yao
Lin, Yen-Ko
Long, Cheng-Yu
Wu, Meng-Ni
Chen, Chao-Ju
Wu, Wen-Jeng
author_facet Chen, Yu-Chen
Liang, Yin-Chi
Ho, Shuo-Jung
Chen, Hao-Wei
Juan, Yung-Shun
Tsai, Wei-Chung
Huang, Shu-Pin
Lee, Jung-Ting
Liu, Yu-Peng
Kao, Chung-Yao
Lin, Yen-Ko
Long, Cheng-Yu
Wu, Meng-Ni
Chen, Chao-Ju
Wu, Wen-Jeng
author_sort Chen, Yu-Chen
collection PubMed
description We investigated the storage lower urinary tract symptoms (LUTS) before and after the first dose of coronavirus disease 2019 (COVID-19) vaccine and the association between pre-vaccinated overactive bladder (OAB) and the worsening of storage LUTS following COVID-19 vaccination. This cross-sectional study in a third-level hospital in Taiwan used the validated pre- and post-vaccinated Overactive Bladder Symptom Score (OABSS). Diagnosis of OAB was made using pre-vaccinated OABSS. The deterioration of storage LUTS was assessed as the increased score of OABSS following vaccination. Of 889 subjects, up to 13.4% experienced worsened storage LUTS after vaccination. OAB was significantly associated with an increased risk of worsening urinary urgency (p = 0.030), frequency (p = 0.027), and seeking medical assistance due to urinary adverse events (p < 0.001) after vaccination. The OAB group faced significantly greater changes in OABSS-urgency (p = 0.003), OABSS-frequency (p = 0.025), and total OABSS (p = 0.014) after vaccination compared to those observed in the non-OAB group. Multivariate regression revealed that pre-vaccinated OAB (p = 0.003) was a risk for the deterioration of storage LUTS. In conclusion, storage LUTS may deteriorate after vaccination. OAB was significantly associated with higher risk and greater changes in worsening storage LUTS. Storage LUTS should be closely monitored after COVID-19 vaccination, especially in those OAB patients.
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spelling pubmed-91481262022-05-29 Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms? Chen, Yu-Chen Liang, Yin-Chi Ho, Shuo-Jung Chen, Hao-Wei Juan, Yung-Shun Tsai, Wei-Chung Huang, Shu-Pin Lee, Jung-Ting Liu, Yu-Peng Kao, Chung-Yao Lin, Yen-Ko Long, Cheng-Yu Wu, Meng-Ni Chen, Chao-Ju Wu, Wen-Jeng J Clin Med Article We investigated the storage lower urinary tract symptoms (LUTS) before and after the first dose of coronavirus disease 2019 (COVID-19) vaccine and the association between pre-vaccinated overactive bladder (OAB) and the worsening of storage LUTS following COVID-19 vaccination. This cross-sectional study in a third-level hospital in Taiwan used the validated pre- and post-vaccinated Overactive Bladder Symptom Score (OABSS). Diagnosis of OAB was made using pre-vaccinated OABSS. The deterioration of storage LUTS was assessed as the increased score of OABSS following vaccination. Of 889 subjects, up to 13.4% experienced worsened storage LUTS after vaccination. OAB was significantly associated with an increased risk of worsening urinary urgency (p = 0.030), frequency (p = 0.027), and seeking medical assistance due to urinary adverse events (p < 0.001) after vaccination. The OAB group faced significantly greater changes in OABSS-urgency (p = 0.003), OABSS-frequency (p = 0.025), and total OABSS (p = 0.014) after vaccination compared to those observed in the non-OAB group. Multivariate regression revealed that pre-vaccinated OAB (p = 0.003) was a risk for the deterioration of storage LUTS. In conclusion, storage LUTS may deteriorate after vaccination. OAB was significantly associated with higher risk and greater changes in worsening storage LUTS. Storage LUTS should be closely monitored after COVID-19 vaccination, especially in those OAB patients. MDPI 2022-05-12 /pmc/articles/PMC9148126/ /pubmed/35628863 http://dx.doi.org/10.3390/jcm11102736 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Yu-Chen
Liang, Yin-Chi
Ho, Shuo-Jung
Chen, Hao-Wei
Juan, Yung-Shun
Tsai, Wei-Chung
Huang, Shu-Pin
Lee, Jung-Ting
Liu, Yu-Peng
Kao, Chung-Yao
Lin, Yen-Ko
Long, Cheng-Yu
Wu, Meng-Ni
Chen, Chao-Ju
Wu, Wen-Jeng
Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title_full Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title_fullStr Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title_full_unstemmed Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title_short Does COVID-19 Vaccination Cause Storage Lower Urinary Tract Symptoms?
title_sort does covid-19 vaccination cause storage lower urinary tract symptoms?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148126/
https://www.ncbi.nlm.nih.gov/pubmed/35628863
http://dx.doi.org/10.3390/jcm11102736
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