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High Efficacy Combined Microneedles Array with Methotrexate Nanocrystals for Effective Anti-Rheumatoid Arthritis

INTRODUCTION: Methotrexate (MTX) is the first-line drug for the treatment of rheumatoid arthritis (RA) in several countries. However, MTX has an extremely low solubility in water, and the side effects caused by its delivery mode restrict its curative effect. In this study, we designed a dissolving m...

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Detalles Bibliográficos
Autores principales:	Wei, Fang, Wang, Qiuyue, Liu, Hang, Yang, Xuejing, Cao, Wenyu, Zhao, Weiman, Li, Yingying, Zheng, Lijie, Ma, Tao, Wang, Qingqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148202/ https://www.ncbi.nlm.nih.gov/pubmed/35637840 http://dx.doi.org/10.2147/IJN.S365523

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