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Cytotoxic and Radiosensitising Effects of a Novel Thioredoxin Reductase Inhibitor in Brain Cancers

The thioredoxin (Trx) system, a key antioxidant pathway, represents an attractive target for cancer therapy. This study investigated the chemotherapeutic and radiosensitising effects of a novel Trx reductase (TrxR) inhibitor, IQ10, on brain cancer cells and the underlying mechanisms of action. Five...

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Detalles Bibliográficos
Autores principales:	Yao, Anqi, Storr, Sarah J., Inman, Martyn, Barwell, Lucy, Moody, Christopher J., Martin, Stewart G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148287/ https://www.ncbi.nlm.nih.gov/pubmed/35344158 http://dx.doi.org/10.1007/s12035-022-02808-4

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