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mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington’s disease phenotype

Glutamate receptors, including mGluR5, are involved in learning and memory impairments triggered by aging and neurological diseases. However, each condition involves distinct molecular mechanisms. It is still unclear whether the mGluR5 cell signaling pathways involved in normal brain aging differ fr...

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Detalles Bibliográficos
Autores principales:	de Souza, Jessica M., Ferreira-Vieira, Talita H., Maciel, Esther M. A., Silva, Nathalia C., Lima, Izabella B. Quirino, Doria, Juliana G., Olmo, Isabella G., Ribeiro, Fabiola M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148310/ https://www.ncbi.nlm.nih.gov/pubmed/35643779 http://dx.doi.org/10.1038/s41598-022-13029-z

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