Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials

Spinal cord injury (SCI) remains an incurable, life-changing neurological condition, causing permanent loss of motor and sensory function in millions of people worldwide and affecting them in every aspect of their personal and social life. In the last two decades, after its success in various fields...

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Autores principales: Damianakis, Emmanouil I, Benetos, Ioannis S, Evangelopoulos, Dimitrios Stergios, Kotroni, Aikaterini, Vlamis, John, Pneumaticos, Spyridon G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Physical Medicine & Rehabilitation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148387/
https://www.ncbi.nlm.nih.gov/pubmed/35664388
http://dx.doi.org/10.7759/cureus.24575
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author Damianakis, Emmanouil I
Benetos, Ioannis S
Evangelopoulos, Dimitrios Stergios
Kotroni, Aikaterini
Vlamis, John
Pneumaticos, Spyridon G
author_facet Damianakis, Emmanouil I
Benetos, Ioannis S
Evangelopoulos, Dimitrios Stergios
Kotroni, Aikaterini
Vlamis, John
Pneumaticos, Spyridon G
author_sort Damianakis, Emmanouil I
collection PubMed
description Spinal cord injury (SCI) remains an incurable, life-changing neurological condition, causing permanent loss of motor and sensory function in millions of people worldwide and affecting them in every aspect of their personal and social life. In the last two decades, after its success in various fields of medicine, stem cell therapy has been investigated in the research field as a potential treatment for SCI. This review focuses on the pathophysiology of SCI, the characteristics of the different stem cell therapies used for its treatment, and the results of these therapies in recently published clinical trials.
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spelling pubmed-91483872022-06-02 Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials Damianakis, Emmanouil I Benetos, Ioannis S Evangelopoulos, Dimitrios Stergios Kotroni, Aikaterini Vlamis, John Pneumaticos, Spyridon G Cureus Physical Medicine & Rehabilitation Spinal cord injury (SCI) remains an incurable, life-changing neurological condition, causing permanent loss of motor and sensory function in millions of people worldwide and affecting them in every aspect of their personal and social life. In the last two decades, after its success in various fields of medicine, stem cell therapy has been investigated in the research field as a potential treatment for SCI. This review focuses on the pathophysiology of SCI, the characteristics of the different stem cell therapies used for its treatment, and the results of these therapies in recently published clinical trials. Cureus 2022-04-28 /pmc/articles/PMC9148387/ /pubmed/35664388 http://dx.doi.org/10.7759/cureus.24575 Text en Copyright © 2022, Damianakis et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Physical Medicine & Rehabilitation
Damianakis, Emmanouil I
Benetos, Ioannis S
Evangelopoulos, Dimitrios Stergios
Kotroni, Aikaterini
Vlamis, John
Pneumaticos, Spyridon G
Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title_full Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title_fullStr Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title_full_unstemmed Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title_short Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials
title_sort stem cell therapy for spinal cord injury: a review of recent clinical trials
topic Physical Medicine & Rehabilitation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148387/
https://www.ncbi.nlm.nih.gov/pubmed/35664388
http://dx.doi.org/10.7759/cureus.24575
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