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Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis

BACKGROUND: Menaquinone-7 (MK-7), which is associated with complex and tightly regulated pathways and redox imbalances, is produced at low titres in Bacillus subtilis. Synthetic biology provides a rational engineering principle for the transcriptional optimisation of key enzymes and the artificial c...

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Detalles Bibliográficos
Autores principales:	Ding, Xiumin, Zheng, Zhiming, Zhao, Genhai, Wang, Li, Wang, Han, Yang, Qiang, Zhang, Mengxue, Li, Luyao, Wang, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148487/ https://www.ncbi.nlm.nih.gov/pubmed/35643569 http://dx.doi.org/10.1186/s12934-022-01823-3

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