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Optimization of the production process for the anticancer lead compound illudin M: improving titers in shake-flasks

BACKGROUND: The fungal sesquiterpenes Illudin M and S are important base molecules for the development of new anticancer agents due to their strong activity against some resistant tumor cell lines. Due to nonspecific toxicity of the natural compounds, improvement of the pharmacophore is required. A...

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Detalles Bibliográficos
Autores principales:	Chaverra-Muñoz, Lillibeth, Briem, Theresa, Hüttel, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148526/ https://www.ncbi.nlm.nih.gov/pubmed/35643529 http://dx.doi.org/10.1186/s12934-022-01827-z

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