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Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system

Traditional Chinese medicine (TCM) has a long history, rich clinical experience, and unique advantages in the prevention and treatment of diseases. The quality and safety of Chinese medicinal materials (CMMs) directly affect the clinical efficacy and development of the TCM industry. However, confuse...

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Autores principales: Zhao, Dazhong, Tian, Zunzhe, Cai, Jing, He, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148530/
https://www.ncbi.nlm.nih.gov/pubmed/35643582
http://dx.doi.org/10.1186/s13020-022-00620-9
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author Zhao, Dazhong
Tian, Zunzhe
Cai, Jing
He, Juan
author_facet Zhao, Dazhong
Tian, Zunzhe
Cai, Jing
He, Juan
author_sort Zhao, Dazhong
collection PubMed
description Traditional Chinese medicine (TCM) has a long history, rich clinical experience, and unique advantages in the prevention and treatment of diseases. The quality and safety of Chinese medicinal materials (CMMs) directly affect the clinical efficacy and development of the TCM industry. However, confused provenance, counterfeiting and adulteration of CMMs hinder the acceptance of its therapeutic benefits in modern society. Therefore, the establishment and improvement of a TCM traceability system would be conducive to the transparency of the CMMs production, distribution, and circulation, thereby improving drug safety and promoting industry development. This review discusses the challenges faced in the development of TCM traceability system, the technologies currently available for tracing CMMs, and the potential application of Barcoded Microbial Spores (BMS) to improve CMMs origin traceability and TCM traceability systems.
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spelling pubmed-91485302022-05-30 Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system Zhao, Dazhong Tian, Zunzhe Cai, Jing He, Juan Chin Med Commentary Traditional Chinese medicine (TCM) has a long history, rich clinical experience, and unique advantages in the prevention and treatment of diseases. The quality and safety of Chinese medicinal materials (CMMs) directly affect the clinical efficacy and development of the TCM industry. However, confused provenance, counterfeiting and adulteration of CMMs hinder the acceptance of its therapeutic benefits in modern society. Therefore, the establishment and improvement of a TCM traceability system would be conducive to the transparency of the CMMs production, distribution, and circulation, thereby improving drug safety and promoting industry development. This review discusses the challenges faced in the development of TCM traceability system, the technologies currently available for tracing CMMs, and the potential application of Barcoded Microbial Spores (BMS) to improve CMMs origin traceability and TCM traceability systems. BioMed Central 2022-05-28 /pmc/articles/PMC9148530/ /pubmed/35643582 http://dx.doi.org/10.1186/s13020-022-00620-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Commentary
Zhao, Dazhong
Tian, Zunzhe
Cai, Jing
He, Juan
Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title_full Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title_fullStr Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title_full_unstemmed Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title_short Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system
title_sort microbial spore genetic marker technology, a potential technology for traditional chinese medicine traceability system
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148530/
https://www.ncbi.nlm.nih.gov/pubmed/35643582
http://dx.doi.org/10.1186/s13020-022-00620-9
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