Exosomal MiR-199a-5p Inhibits Tumorigenesis and Angiogenesis by Targeting VEGFA in Osteosarcoma

BACKGROUND: Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents. microRNAs have been found to play a vital role in tumor angiogenesis. Here, we investigated the effects of miR-199a-5p on tumor growth and angiogenesis in osteosarcoma. Furthermore, the underlying m...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Cao, Hongxin, Gu, Guanghui, Hou, Dehui, You, Yunhao, Li, Xiang, Chen, Yunzhen, Jiao, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148962/
https://www.ncbi.nlm.nih.gov/pubmed/35651811
http://dx.doi.org/10.3389/fonc.2022.884559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148962/
https://www.ncbi.nlm.nih.gov/pubmed/35651811
http://dx.doi.org/10.3389/fonc.2022.884559

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