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Exosomal MiR-199a-5p Inhibits Tumorigenesis and Angiogenesis by Targeting VEGFA in Osteosarcoma
BACKGROUND: Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents. microRNAs have been found to play a vital role in tumor angiogenesis. Here, we investigated the effects of miR-199a-5p on tumor growth and angiogenesis in osteosarcoma. Furthermore, the underlying m...
Autores principales: | Zhang, Lu, Cao, Hongxin, Gu, Guanghui, Hou, Dehui, You, Yunhao, Li, Xiang, Chen, Yunzhen, Jiao, Guangjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148962/ https://www.ncbi.nlm.nih.gov/pubmed/35651811 http://dx.doi.org/10.3389/fonc.2022.884559 |
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