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Survival of HT29 Cancer Cells Is Affected by IGF1R Inhibition via Modulation of Self-DNA-Triggered TLR9 Signaling and the Autophagy Response

Purpose: In HT29 colon cancer cells, a close interplay between self-DNA-induced TLR9 signaling and autophagy response was found, with remarkable effects on cell survival and differentiation. IGF1R activation drives the development and malignant progression of colorectal cancer. IGF1R inhibition disp...

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Detalles Bibliográficos
Autores principales:	Sipos, Ferenc, Bohusné Barta, Bettina, Simon, Ágnes, Nagy, Lőrinc, Dankó, Titanilla, Raffay, Regina Eszter, Petővári, Gábor, Zsiros, Viktória, Wichmann, Barnabás, Sebestyén, Anna, Műzes, Györgyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pathology and Oncology Archive
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148969/ https://www.ncbi.nlm.nih.gov/pubmed/35651701 http://dx.doi.org/10.3389/pore.2022.1610322

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