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Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor

BACKGROUND: Transcatheter aortic valve implantation (TAVI) is associated with new onset brady- and tachyarrhythmias which may impact clinical outcome. AIMS: To investigate the true incidence of new onset arrhythmias within 12 months after TAVI using an implantable cardiac monitor (ICM). METHODS: One...

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Autores principales: Nozica, Nikolas, Siontis, George C. M., Elchinova, Elena Georgieva, Goulouti, Eleni, Asami, Masahiko, Bartkowiak, Joanna, Baldinger, Samuel, Servatius, Helge, Seiler, Jens, Tanner, Hildegard, Noti, Fabian, Haeberlin, Andreas, Branca, Mattia, Lanz, Jonas, Stortecky, Stefan, Pilgrim, Thomas, Windecker, Stephan, Reichlin, Tobias, Praz, Fabien, Roten, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149277/
https://www.ncbi.nlm.nih.gov/pubmed/35651903
http://dx.doi.org/10.3389/fcvm.2022.876546
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author Nozica, Nikolas
Siontis, George C. M.
Elchinova, Elena Georgieva
Goulouti, Eleni
Asami, Masahiko
Bartkowiak, Joanna
Baldinger, Samuel
Servatius, Helge
Seiler, Jens
Tanner, Hildegard
Noti, Fabian
Haeberlin, Andreas
Branca, Mattia
Lanz, Jonas
Stortecky, Stefan
Pilgrim, Thomas
Windecker, Stephan
Reichlin, Tobias
Praz, Fabien
Roten, Laurent
author_facet Nozica, Nikolas
Siontis, George C. M.
Elchinova, Elena Georgieva
Goulouti, Eleni
Asami, Masahiko
Bartkowiak, Joanna
Baldinger, Samuel
Servatius, Helge
Seiler, Jens
Tanner, Hildegard
Noti, Fabian
Haeberlin, Andreas
Branca, Mattia
Lanz, Jonas
Stortecky, Stefan
Pilgrim, Thomas
Windecker, Stephan
Reichlin, Tobias
Praz, Fabien
Roten, Laurent
author_sort Nozica, Nikolas
collection PubMed
description BACKGROUND: Transcatheter aortic valve implantation (TAVI) is associated with new onset brady- and tachyarrhythmias which may impact clinical outcome. AIMS: To investigate the true incidence of new onset arrhythmias within 12 months after TAVI using an implantable cardiac monitor (ICM). METHODS: One hundred patients undergoing TAVI received an ICM within 3 months before or up to 5 days after TAVI. Patients were followed-up for 12 months after discharge from TAVI for the occurrence of atrial fibrillation (AF), bradycardia (≤30 bpm), advanced atrioventricular (AV) block, sustained ventricular and supraventricular tachycardia. RESULTS: A previously undiagnosed arrhythmia was observed in 31 patients (31%) and comprised AF in 19 patients (19%), advanced AV block in 3 patients (3%), and sustained supraventricular and ventricular tachycardia in 10 (10%) and 2 patients (2%), respectively. Three patients had a clinical diagnosis of sick-sinus-syndrome. A permanent pacemaker (PPM) was implanted in six patients (6%). The prevalence of pre-existing AF was 28%, and 47% of the patients had AF at the end of the study period. AF burden was significantly higher in patients with pre-existing [26.7% (IQR 0.3%; 100%)] compared to patients with new-onset AF [0.0% (IQR 0.0%; 0.06%); p = 0.001]. Three patients died after TAVI without evidence of an arrhythmic cause according to the available ICM recordings. CONCLUSIONS: Rhythm monitoring for 12 months after TAVI revealed new arrhythmias, mainly AF, in almost one third of patients. Atrial fibrillation burden was higher in patients with prevalent compared to incident AF. Selected patients may benefit from short-term remote monitoring. TRIAL REGISTRATION: https://clinicaltrials.gov/: NCT02559011.
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spelling pubmed-91492772022-05-31 Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor Nozica, Nikolas Siontis, George C. M. Elchinova, Elena Georgieva Goulouti, Eleni Asami, Masahiko Bartkowiak, Joanna Baldinger, Samuel Servatius, Helge Seiler, Jens Tanner, Hildegard Noti, Fabian Haeberlin, Andreas Branca, Mattia Lanz, Jonas Stortecky, Stefan Pilgrim, Thomas Windecker, Stephan Reichlin, Tobias Praz, Fabien Roten, Laurent Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Transcatheter aortic valve implantation (TAVI) is associated with new onset brady- and tachyarrhythmias which may impact clinical outcome. AIMS: To investigate the true incidence of new onset arrhythmias within 12 months after TAVI using an implantable cardiac monitor (ICM). METHODS: One hundred patients undergoing TAVI received an ICM within 3 months before or up to 5 days after TAVI. Patients were followed-up for 12 months after discharge from TAVI for the occurrence of atrial fibrillation (AF), bradycardia (≤30 bpm), advanced atrioventricular (AV) block, sustained ventricular and supraventricular tachycardia. RESULTS: A previously undiagnosed arrhythmia was observed in 31 patients (31%) and comprised AF in 19 patients (19%), advanced AV block in 3 patients (3%), and sustained supraventricular and ventricular tachycardia in 10 (10%) and 2 patients (2%), respectively. Three patients had a clinical diagnosis of sick-sinus-syndrome. A permanent pacemaker (PPM) was implanted in six patients (6%). The prevalence of pre-existing AF was 28%, and 47% of the patients had AF at the end of the study period. AF burden was significantly higher in patients with pre-existing [26.7% (IQR 0.3%; 100%)] compared to patients with new-onset AF [0.0% (IQR 0.0%; 0.06%); p = 0.001]. Three patients died after TAVI without evidence of an arrhythmic cause according to the available ICM recordings. CONCLUSIONS: Rhythm monitoring for 12 months after TAVI revealed new arrhythmias, mainly AF, in almost one third of patients. Atrial fibrillation burden was higher in patients with prevalent compared to incident AF. Selected patients may benefit from short-term remote monitoring. TRIAL REGISTRATION: https://clinicaltrials.gov/: NCT02559011. Frontiers Media S.A. 2022-05-16 /pmc/articles/PMC9149277/ /pubmed/35651903 http://dx.doi.org/10.3389/fcvm.2022.876546 Text en Copyright © 2022 Nozica, Siontis, Elchinova, Goulouti, Asami, Bartkowiak, Baldinger, Servatius, Seiler, Tanner, Noti, Haeberlin, Branca, Lanz, Stortecky, Pilgrim, Windecker, Reichlin, Praz and Roten. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Nozica, Nikolas
Siontis, George C. M.
Elchinova, Elena Georgieva
Goulouti, Eleni
Asami, Masahiko
Bartkowiak, Joanna
Baldinger, Samuel
Servatius, Helge
Seiler, Jens
Tanner, Hildegard
Noti, Fabian
Haeberlin, Andreas
Branca, Mattia
Lanz, Jonas
Stortecky, Stefan
Pilgrim, Thomas
Windecker, Stephan
Reichlin, Tobias
Praz, Fabien
Roten, Laurent
Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title_full Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title_fullStr Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title_full_unstemmed Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title_short Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
title_sort assessment of new onset arrhythmias after transcatheter aortic valve implantation using an implantable cardiac monitor
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149277/
https://www.ncbi.nlm.nih.gov/pubmed/35651903
http://dx.doi.org/10.3389/fcvm.2022.876546
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