Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity

T cell-mediated immunity plays a central role in the control and clearance of intracellular Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel T cell-targeted vaccine that induces pathogen-specific cell-mediated immunity to protect against Q fever in humans...

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Detalles Bibliográficos
Autores principales: Sluder, Ann E., Raju Paul, Susan, Moise, Leonard, Dold, Christina, Richard, Guilhem, Silva-Reyes, Laura, Baeten, Laurie A., Scholzen, Anja, Reeves, Patrick M., Pollard, Andrew J., Garritsen, Anja, Bowen, Richard A., De Groot, Anne S., Rollier, Christine, Poznansky, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149306/
https://www.ncbi.nlm.nih.gov/pubmed/35651616
http://dx.doi.org/10.3389/fimmu.2022.901372

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