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ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia

Heightened platelet phagocytosis by macrophages accompanied by an increase in IFN-γ play key roles in the etiology of immune thrombocytopenia (ITP); however, it remains elusive how macrophage-mediated platelet clearance is regulated in ITP. Here, we report that adhesion and degranulation-protein ada...

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Detalles Bibliográficos
Autores principales: Xiong, Yiwei, Li, Yanli, Cui, Xinxing, Zhang, Lifeng, Yang, Xiaodong, Liu, Hebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149338/
https://www.ncbi.nlm.nih.gov/pubmed/35637282
http://dx.doi.org/10.1038/s41423-022-00881-2