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ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia
Heightened platelet phagocytosis by macrophages accompanied by an increase in IFN-γ play key roles in the etiology of immune thrombocytopenia (ITP); however, it remains elusive how macrophage-mediated platelet clearance is regulated in ITP. Here, we report that adhesion and degranulation-protein ada...
Autores principales: | Xiong, Yiwei, Li, Yanli, Cui, Xinxing, Zhang, Lifeng, Yang, Xiaodong, Liu, Hebin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149338/ https://www.ncbi.nlm.nih.gov/pubmed/35637282 http://dx.doi.org/10.1038/s41423-022-00881-2 |
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