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Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma
OBJECTIVES: To determine the prognostic significance of nodal yield in patients with clinically node-negative (cN0) oral cavity squamous cell carcinoma (OCSCC). METHODS: This retrospective observational study included 40 patients with cN0 OCSCC who underwent treatment with at least 6 months of follo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Saudi Medical Journal
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149762/ https://www.ncbi.nlm.nih.gov/pubmed/34853142 http://dx.doi.org/10.15537/smj.2021.42.12.20210572 |
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author | AlTuwaijri, Ahmad A. Alessa, Mohammed A. Abuhaimed, Alanoud A. Bedaiwi, Reenad H. Almayouf, Mohammad A. Albarrak, Majed M. Aldhahri, Saleh F. Al-Qahtani, Khalid H. |
author_facet | AlTuwaijri, Ahmad A. Alessa, Mohammed A. Abuhaimed, Alanoud A. Bedaiwi, Reenad H. Almayouf, Mohammad A. Albarrak, Majed M. Aldhahri, Saleh F. Al-Qahtani, Khalid H. |
author_sort | AlTuwaijri, Ahmad A. |
collection | PubMed |
description | OBJECTIVES: To determine the prognostic significance of nodal yield in patients with clinically node-negative (cN0) oral cavity squamous cell carcinoma (OCSCC). METHODS: This retrospective observational study included 40 patients with cN0 OCSCC who underwent treatment with at least 6 months of follow-up data from November 2012 to April 2020. We recorded the variables, including patient demographics, cancer site, tumor-node-metastasis (TNM) staging, type of treatment, lymph node yield (LNY), histopathologic diagnosis, and recurrence. The recorded data were analyzed with descriptive and interferential statistics using specific tests. RESULTS: Our study cohort comprised of 27 males and 13 females with a mean age of 60.08+13.153 years. Tongue (55%) was the commonly affected site. Seventeen (42.5%) patients belonged to TNM stage II. The mean LNY in our study was 38.65±25.41 (range 7-98). Following surgery, 19 (47.5%) patients further received adjuvant therapies. Recurrence was reported only in 4 (10%) patients. There was no significant difference between LNY and recurrence rate (p=0.892). Factors including, age (p=0.121), gender (p=0.209), site (p=0.519), size of tumor (p=0.416) did not influence the LNY. CONCLUSION: There is no correlation between LNY and recurrence in cN0 OCSCC patients in our study. Meticulous neck dissection and thorough pathologic reporting prevents TNM under staging and improves the overall survival and prognosis. |
format | Online Article Text |
id | pubmed-9149762 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Saudi Medical Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-91497622022-06-23 Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma AlTuwaijri, Ahmad A. Alessa, Mohammed A. Abuhaimed, Alanoud A. Bedaiwi, Reenad H. Almayouf, Mohammad A. Albarrak, Majed M. Aldhahri, Saleh F. Al-Qahtani, Khalid H. Saudi Med J Brief Communication OBJECTIVES: To determine the prognostic significance of nodal yield in patients with clinically node-negative (cN0) oral cavity squamous cell carcinoma (OCSCC). METHODS: This retrospective observational study included 40 patients with cN0 OCSCC who underwent treatment with at least 6 months of follow-up data from November 2012 to April 2020. We recorded the variables, including patient demographics, cancer site, tumor-node-metastasis (TNM) staging, type of treatment, lymph node yield (LNY), histopathologic diagnosis, and recurrence. The recorded data were analyzed with descriptive and interferential statistics using specific tests. RESULTS: Our study cohort comprised of 27 males and 13 females with a mean age of 60.08+13.153 years. Tongue (55%) was the commonly affected site. Seventeen (42.5%) patients belonged to TNM stage II. The mean LNY in our study was 38.65±25.41 (range 7-98). Following surgery, 19 (47.5%) patients further received adjuvant therapies. Recurrence was reported only in 4 (10%) patients. There was no significant difference between LNY and recurrence rate (p=0.892). Factors including, age (p=0.121), gender (p=0.209), site (p=0.519), size of tumor (p=0.416) did not influence the LNY. CONCLUSION: There is no correlation between LNY and recurrence in cN0 OCSCC patients in our study. Meticulous neck dissection and thorough pathologic reporting prevents TNM under staging and improves the overall survival and prognosis. Saudi Medical Journal 2021-12 /pmc/articles/PMC9149762/ /pubmed/34853142 http://dx.doi.org/10.15537/smj.2021.42.12.20210572 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. |
spellingShingle | Brief Communication AlTuwaijri, Ahmad A. Alessa, Mohammed A. Abuhaimed, Alanoud A. Bedaiwi, Reenad H. Almayouf, Mohammad A. Albarrak, Majed M. Aldhahri, Saleh F. Al-Qahtani, Khalid H. Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title | Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title_full | Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title_fullStr | Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title_full_unstemmed | Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title_short | Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
title_sort | lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149762/ https://www.ncbi.nlm.nih.gov/pubmed/34853142 http://dx.doi.org/10.15537/smj.2021.42.12.20210572 |
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