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When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma

Background: Pheochromocytoma is known for its instantaneous presentation, especially in the younger population. Hemodynamic instability may be the cause of severe complications and impede patients’ ability to undergo surgical treatment. These tumours are surgically difficult to treat due to the risk...

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Autores principales: Baio, Raffaele, Pagano, Tommaso, Molisso, Giovanni, Di Mauro, Umberto, Intilla, Olivier, Albano, Francesco, Scarpato, Fulvio, Giacometti, Stefania, Sanseverino, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149903/
https://www.ncbi.nlm.nih.gov/pubmed/35645250
http://dx.doi.org/10.3390/diseases10020029
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author Baio, Raffaele
Pagano, Tommaso
Molisso, Giovanni
Di Mauro, Umberto
Intilla, Olivier
Albano, Francesco
Scarpato, Fulvio
Giacometti, Stefania
Sanseverino, Roberto
author_facet Baio, Raffaele
Pagano, Tommaso
Molisso, Giovanni
Di Mauro, Umberto
Intilla, Olivier
Albano, Francesco
Scarpato, Fulvio
Giacometti, Stefania
Sanseverino, Roberto
author_sort Baio, Raffaele
collection PubMed
description Background: Pheochromocytoma is known for its instantaneous presentation, especially in the younger population. Hemodynamic instability may be the cause of severe complications and impede patients’ ability to undergo surgical treatment. These tumours are surgically difficult to treat due to the risk of catecholamine release during their manipulations, and when they are large, the tumour size represents an additional challenge. In our report, cardiogenic shock developed due to increases in systemic vascular resistance, and the lesion’s size induced surgeons to perform open surgery. Case presentation: A 46-year-old female patient was admitted to our intensive care unit with hypertension and later cardiogenic shock. Systolic dysfunction was noted, along with severely increased systemic vascular resistance. A CT scan showed a left-sided 8.5 cm adrenal mass, which was confirmed as pheochromocytoma using meta-iodobenzylguanidine scintigraphy. Anaesthesiologists and the surgical team planned an effective strategy of treatment. Given the lesion’s size and its apparent invasion of the neighbouring organs, open adrenalectomy (after prolonged hemodynamic stabilisation) was considered safer. The surgery was successful, and the patient remains free from disease two years after the initial event. Conclusions: Large pheochromocytoma can be safely and effectively treated with open surgery by experienced hands but only by seeking to reach hemodynamic stabilisation and minimising the release of catecholamine before and during surgery.
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spelling pubmed-91499032022-05-31 When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma Baio, Raffaele Pagano, Tommaso Molisso, Giovanni Di Mauro, Umberto Intilla, Olivier Albano, Francesco Scarpato, Fulvio Giacometti, Stefania Sanseverino, Roberto Diseases Technical Note Background: Pheochromocytoma is known for its instantaneous presentation, especially in the younger population. Hemodynamic instability may be the cause of severe complications and impede patients’ ability to undergo surgical treatment. These tumours are surgically difficult to treat due to the risk of catecholamine release during their manipulations, and when they are large, the tumour size represents an additional challenge. In our report, cardiogenic shock developed due to increases in systemic vascular resistance, and the lesion’s size induced surgeons to perform open surgery. Case presentation: A 46-year-old female patient was admitted to our intensive care unit with hypertension and later cardiogenic shock. Systolic dysfunction was noted, along with severely increased systemic vascular resistance. A CT scan showed a left-sided 8.5 cm adrenal mass, which was confirmed as pheochromocytoma using meta-iodobenzylguanidine scintigraphy. Anaesthesiologists and the surgical team planned an effective strategy of treatment. Given the lesion’s size and its apparent invasion of the neighbouring organs, open adrenalectomy (after prolonged hemodynamic stabilisation) was considered safer. The surgery was successful, and the patient remains free from disease two years after the initial event. Conclusions: Large pheochromocytoma can be safely and effectively treated with open surgery by experienced hands but only by seeking to reach hemodynamic stabilisation and minimising the release of catecholamine before and during surgery. MDPI 2022-05-17 /pmc/articles/PMC9149903/ /pubmed/35645250 http://dx.doi.org/10.3390/diseases10020029 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Technical Note
Baio, Raffaele
Pagano, Tommaso
Molisso, Giovanni
Di Mauro, Umberto
Intilla, Olivier
Albano, Francesco
Scarpato, Fulvio
Giacometti, Stefania
Sanseverino, Roberto
When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title_full When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title_fullStr When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title_full_unstemmed When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title_short When a Multidisciplinary Approach Is Life-Saving: A Case Report of Cardiogenic Shock Induced by a Large Pheochromocytoma
title_sort when a multidisciplinary approach is life-saving: a case report of cardiogenic shock induced by a large pheochromocytoma
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149903/
https://www.ncbi.nlm.nih.gov/pubmed/35645250
http://dx.doi.org/10.3390/diseases10020029
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