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Quantitative Structure–Activity Relationship (QSAR) Study Predicts Small-Molecule Binding to RNA Structure

[Image: see text] The diversity of RNA structural elements and their documented role in human diseases make RNA an attractive therapeutic target. However, progress in drug discovery and development has been hindered by challenges in the determination of high-resolution RNA structures and a limited u...

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Detalles Bibliográficos
Autores principales:	Cai, Zhengguo, Zafferani, Martina, Akande, Olanrewaju M., Hargrove, Amanda E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150105/ https://www.ncbi.nlm.nih.gov/pubmed/35522972 http://dx.doi.org/10.1021/acs.jmedchem.2c00254

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