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Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale
[Image: see text] The canonical Wingless-related integration site signaling pathway plays a critical role in human physiology, and its dysregulation can lead to an array of diseases. β-Catenin is a multifunctional protein within this pathway and an attractive yet challenging therapeutic target, most...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150122/ https://www.ncbi.nlm.nih.gov/pubmed/35581674 http://dx.doi.org/10.1021/acs.jmedchem.2c00228 |