Cargando…

N-Acetyl-Cysteinylated Streptophenazines from Streptomyces

[Image: see text] Here, we describe two N-acetyl-cysteinylated streptophenazines (1 and 2) produced by the soil-derived Streptomyces sp. ID63040 and identified through a metabolomic approach. These metabolites attracted our interest due to their low occurrence frequency in a large library of ferment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vind, Kristiina, Maffioli, Sonia, Fernandez Ciruelos, Blanca, Waschulin, Valentin, Brunati, Cristina, Simone, Matteo, Sosio, Margherita, Donadio, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150181/ https://www.ncbi.nlm.nih.gov/pubmed/35422124 http://dx.doi.org/10.1021/acs.jnatprod.1c01123

Ejemplares similares

Megalochelin, a Tridecapeptide Siderophore from a Talented Streptomycete
por: Vind, Kristiina, et al.
Publicado: (2023)

Effective approaches to discover new microbial metabolites in a large strain library
por: Zdouc, Mitja M, et al.
Publicado: (2021)

Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells
por: Brunati, Cristina, et al.
Publicado: (2018)

Allopeptimicins: unique antibacterial metabolites generated by hybrid PKS-NRPS, with original self-defense mechanism in Actinoallomurus
por: Iorio, Marianna, et al.
Publicado: (2022)

Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain
por: Iorio, Marianna, et al.
Publicado: (2021)

Novel Polyethers from Screening Actinoallomurus spp.
por: Iorio, Marianna, et al.
Publicado: (2018)

Discovering new bioactive molecules from microbial sources
por: Monciardini, Paolo, et al.
Publicado: (2014)

Nature’s Lab for Derivatization: New and Revised Structures of a Variety of Streptophenazines Produced by a Sponge-Derived Streptomyces Strain
por: Kunz, Anna Lena, et al.
Publicado: (2014)

Planomonospora: A Metabolomics Perspective on an Underexplored Actinobacteria Genus
por: Zdouc, Mitja M., et al.
Publicado: (2021)

Design and validation of a PCR screen for γ-butyrolactone-like regulatory systems in Streptomyces
por: Waschulin, Valentin, et al.
Publicado: (2023)

Complex Regulatory Networks Governing Production of the Glycopeptide A40926
por: Alduina, Rosa, et al.
Publicado: (2018)

Biosynthetic potential of uncultured Antarctic soil bacteria revealed through long-read metagenomic sequencing
por: Waschulin, Valentin, et al.
Publicado: (2021)

Cysteinyl Leukotriene Pathway and Cancer
por: Tsai, Ming-Ju, et al.
Publicado: (2021)

Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts
por: Kanaoka, Yoshihide, et al.
Publicado: (2014)

Adipokines and Cysteinyl Leukotrienes in the Pathogenesis of Asthma
por: Coffey, Michael J., et al.
Publicado: (2015)

Cysteinyl-Leukotriene Receptors and Cellular Signals
por: Rovati, G. Enrico, et al.
Publicado: (2007)

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
por: Marin, Egor, et al.
Publicado: (2020)

A Two-Component regulatory system with opposite effects on glycopeptide antibiotic biosynthesis and resistance
por: Alduina, Rosa, et al.
Publicado: (2020)

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
por: Gusach, Anastasiia, et al.
Publicado: (2019)

Cysteinyl Cathepsins: Multifunctional Enzymes in Cardiovascular Disease
por: Li, Xiang, et al.
Publicado: (2012)

Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control
por: Noronha, Letícia Paula Trajano, et al.
Publicado: (2023)

Cysteinyl Leukotriene and Systemic Inflammatory Levels in Preeclampsia
por: Guzeltas, Gokhan, et al.
Publicado: (2023)

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs
por: Luginina, Aleksandra, et al.
Publicado: (2019)

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
por: Marin, Egor, et al.
Publicado: (2020)

Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments
por: Zhang, Meng, et al.
Publicado: (2022)

Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct
por: Flinspach, Katrin, et al.
Publicado: (2014)

Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis
por: Peters-Golden, M, et al.
Publicado: (2006)

Cysteinyl-glycine in the control of glutathione homeostasis in bovine lenses
por: De Donatis, Gian Marco, et al.
Publicado: (2010)

Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases
por: Gelosa, Paolo, et al.
Publicado: (2017)

Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases
por: Colazzo, Francesca, et al.
Publicado: (2017)

Cysteinyl and methionyl redox switches: Structural prerequisites and consequences
por: Bodnar, Yana, et al.
Publicado: (2023)

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
por: Barrett, Nora A., et al.
Publicado: (2011)

Montelukast: More than a Cysteinyl Leukotriene Receptor Antagonist?
por: Tintinger, Gregory R., et al.
Publicado: (2010)

Can cysteinyl cathepsin activity control diet-induced NAFLD?
por: Yu, Chenglin, et al.
Publicado: (2020)

Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction)
por: Busti, Elena, et al.
Publicado: (2002)

Glutathionylation of beta-actin via a cysteinyl sulfenic acid intermediary
por: Johansson, Magnus, et al.
Publicado: (2007)

Cysteinyl-tRNA Deacylation Can Be Uncoupled from Protein Synthesis
por: David, Alexandre, et al.
Publicado: (2012)

Cysteinyl Peptide Capture for Shotgun Proteomics: Global Assessment of Chemoselective Fractionation
por: Lin, De, et al.
Publicado: (2010)

Characterisation of P2Y(12) Receptor Responsiveness to Cysteinyl Leukotrienes
por: Foster, Holly R., et al.
Publicado: (2013)

Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis
por: Ravishankar, Sudha, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gn0vga22u4if01ddkhersjft6u