Podocyte specific deletion of PKM2 ameliorates LPS-induced podocyte injury through beta-catenin

BACKGROUND: Acute kidney injury (AKI) is associated with a severe decline in kidney function caused by abnormalities within the podocytes' glomerular matrix. Recently, AKI has been linked to alterations in glycolysis and the activity of glycolytic enzymes, including pyruvate kinase M2 (PKM2). H...

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Detalles Bibliográficos
Autores principales: Alquraishi, Mohammed, Chahed, Samah, Alani, Dina, Puckett, Dexter L., Dowker, Presley D., Hubbard, Katelin, Zhao, Yi, Kim, Ji Yeon, Nodit, Laurentia, Fatima, Huma, Donohoe, Dallas, Voy, Brynn, Chowanadisai, Winyoo, Bettaieb, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150347/
https://www.ncbi.nlm.nih.gov/pubmed/35637461
http://dx.doi.org/10.1186/s12964-022-00884-6

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