Cargando…
CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress
BACKGROUND/AIMS: Published evidence implicates Caspase recruitment domain containing protein 9 (CARD9) in innate immunity. Given its recently suggested roles in obesity and insulin resistance, we investigated its regulatory role(s) in the onset of islet beta cell dysfunction under chronic hyperglyce...
Autores principales: | Gamage, Suhadinie, Hali, Mirabela, Chen, Fei, Kowluru, Anjaneyulu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150799/ https://www.ncbi.nlm.nih.gov/pubmed/35362297 http://dx.doi.org/10.33594/000000508 |
Ejemplares similares
-
Hyperglycemic Conditions Promote Rac1-Mediated Serine536 Phosphorylation of p65 Subunit of NFκB (RelA) in Pancreatic Beta Cells
por: Kowluru, Anjaneyulu, et al.
Publicado: (2022) -
Regulatory Roles of Histone Deacetylation in Metabolic Stress-Induced Expression of Caspase Recruitment Domain-Containing Protein 9 (CARD9) in Pancreatic β-Cells
por: Hali, Mirabela, et al.
Publicado: (2023) -
P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells
por: Thamilselvan, Vijayalakshmi, et al.
Publicado: (2020) -
Oxidative Stress in Cytokine-Induced Dysfunction of the Pancreatic Beta Cell: Known Knowns and Known Unknowns
por: Kowluru, Anjaneyulu
Publicado: (2020) -
Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis
por: Meda Venkata, Sai Pranathi, et al.
Publicado: (2022)