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Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells

OBJECTIVE(S): Gemcitabine is a first-line drug for the treatment of bladder cancer. One of the most important mechanisms of gemcitabine resistance is the low expression of cellular membrane transporter hENT1. Various derivatives containing fatty acid side chains have been developed in order to facil...

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Detalles Bibliográficos
Autores principales: Wang, Hongxia, Shao, Zhiyu, Xu, Zhiwen, Ye, Binghao, Li, Ming, Zheng, Qiaoqiao, Ma, Xingyuan, Shi, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150810/
https://www.ncbi.nlm.nih.gov/pubmed/35656081
http://dx.doi.org/10.22038/IJBMS.2022.61118.13528